Jet Breaker™ & JetMixer™ System


Jet Breaker is a semi-automated system for breaking up powder clumps and lumps to ensure superior mixing of powders in pharmaceutical and biopharmaceutical applications.

ILC Dover’s JetBreaker™ is designed for the deagglomeration of difficult-to-mix pharmaceutical and biopharmaceutical powders. By rapidly reducing powder blocks to particles smaller than 10 mm, JetBreaker™ keeps processes moving, eliminates timely and manual delumping efforts, prevents damage to costly process valves, tanks, and other equipment, and ultimately protects the batch of finished pharmaceutical or biopharmaceutical product. Moreover, once a biopharmaceutical powder goes through the JetBreaker™, it can freely flow into JetMixer system with rapid dissolution.

Why JetBreaker™ from ILC Dover?

Efficient Solution

Quickly breaks up clumps into flowable granules to move them to the mixing process.

Superior Quality

High deagglomeration efficiency reduces powder blocks to particles smaller than 10 mm.

Convenient System

In-line or stand-alone unit offers a low footprint and directly connects with a reactor.

The JetMixer System provides fast powder mixing and complete protection of powder properties.

The efficient mixing of powders into liquids is a crucial step in profitable biopharmaceutical manufacturing. For operations where low shear and high product integrity are required, no other technology performs as well as the JetMixer™ System from ILC Dover. JetMixer consists of a few cleverly-designed, elegantly-simple components. A lobe-type, positive-displacement pump typically provides the driving force needed for operation. With its one moving part, the pump remains easy to clean, simple to maintain, and long-lived. In addition to the standard compact, mobile, and fixed skid-mounted forms, JetMixer™ can be easily configured to conform to dust-free process environments. It can be supplied with components fully compatible with nitrogen blanketing and other inert-gas protection protocols, as well as jacketing suitable for heating or cooling, depending on process requirements.

Why JetMixer System from ILC Dover?

Patented Venturi Nozzle

This flat, accelerated jet introduces powder into the liquid stream without clumping, shearing, or heating.

Property Preservation

No shear forces exerted on the powder and insignificant product heating, preserving the powder’s properties.

Superior Mixing

Particle-by-particle introduction of powder via strong vacuum helps prevent bridging and improves mixing.

Range of Viscosities

JetMixer™ can handle operating viscosities ranging from 1 cP to 20,000 cP.

Low Energy Consumption

Small footprint with low energy consumption helps keep operating costs under control.

Improved Ergonomics

It is optional to operate at floor level for improved ergonomics and better worker safety.

Meets Requirements

Design makes it easy to meet WIP/CIP (wash-in-place)/(clean-in-place) requirements.


Patented Venturi/Nozzle System

The patented JetMixer nozzle system creates a flat accelerated jet that draws a surprising amount of powder into the liquid stream without introducing clumping, shearing, or heating. The hopper system and constant level of venturi-generated vacuum assure particle-by-particle induction and mixing, even with high-viscosity fluids. The system works equally well for mixing solid suspensions into liquids or for liquid-liquid mixing. In all cases, the components are uniformly mixed to form a homogeneous fluid.

System Components

The venturi system and mixing chamber contain no moving parts while featuring smooth, polished flow channels and a lack of crevices, edges, or other impediments to WIP/CIP operations. Its inherently smooth geometry makes the system particularly suited for biopharmaceutical processes where CIP is a must and cross-contamination can imperil large amounts of high-value product. The all-stainless-steel system is robust, capable of operating at very low vacuum and process temperatures to 70°C (158°F).

Auxiliary Equipment

Where powders to be mixed tend to clump or aggregate, ILC Dover offers its JetBreaker homogenizers that can delump powders and continuously agitate the hopper to improve flow rate and normalize injector feeding.


  • Media & Buffer Mixing
  • Sodium Chloride
  • Ammonium Sulfide
  • Other Difficult-to-Mix Powders

Contact Us About Powder Containment